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Acquired clinical resistance to vemurafenib, a selective BRAF VE inhibitor, arises frequently after short-term chemotherapy. We hypothesized that a combined therapy using vemurafenib with a G 2 -M phase blocking agent will trap resistant cells and overcome vemurafenib resistance. We then developed an ARF21 subline with significant acquired resistance to vemurafenib and confirmed the strong synergistic effect.

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The naughty former nurse told friends she'd expected the pictures to be computer-altered to conceal her boobs. By Sunday People. Get the biggest celebs stories by email Subscribe See our privacy notice More newsletters.

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Sign in. I'm Abi : I guess none of you know that I trained as an actor for three years.

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GOA — Elisabeth Ramnacher, a German who prefers to go by the name Yogini, wanted to show her employees what Goa used to look like back in its hippie days. When hippies traveled overland from Europe to India decades ago, Goa was often the final stop on the trail, welcoming to its beaches Westerners who wanted to drop out in a place where living was cheap, drugs plentiful and swimming nude the norm. Ramnacher, 58, who first came in the s and now owns the popular Villa Blanche cafe here in Goa.

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As our Santa- sational pictures prove, the TV babe looks fabulous in just a fun fur hat and stole. Abi, 28, says: "I'm very much single at the moment but I'd love to spend Christmas in front of a log fire, naked with the man of my dreams and a glass of mulled wine. By Sunday People.

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SerebralTraveler Plans D. We at Serebral Traveler would love to know if the New York Times — Travel article was helpful, leave a comment, like and share. GOA — Elisabeth Ramnacher, a German who prefers to go by the name Yogini, wanted to show her employees what Goa used to look like back in its hippie days. When hippies traveled overland from Europe to India decades ago, Goa was often the final stop on the trail, welcoming to its beaches Westerners who wanted to drop out in a place where living was cheap, drugs plentiful and swimming nude the norm.

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