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The present study was conducted to explore whether single nucleotide polymorphisms SNPs in Th1 and Th17 cell-mediated immune response genes differentially influence the risk of rheumatoid arthritis RA in women and men. This model consisted of Dectin-2 rs and Dectin-2 rs SNPs and suggested a synergistic effect between the variants. Rheumatoid arthritis RA is an autoimmune disease characterized by chronic inflammatory activity in the synovial joints often leading to progressive cartilage and bone destruction [1].

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Urinary cadmium Cd excretion is associated with cancer and cardiovascular morbidity. A potential mechanism could be disturbance of steroidogenesis in gonads and adrenal glands. We tested whether urinary excretion of Cd is correlated with that of cortico- and sex steroid metabolites in the general adult population.

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